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Sores, lumps, or ulcers on the vulva that do not go away. Pain in the pelvis, especially during urination or sex. [7] Typically, a lesion presents in the form of a lump or ulcer on the labia majora and may be associated with itching, irritation, local bleeding or discharge, in addition to pain with urination or pain during sexual intercourse. [8]
Vulvar tumors are those neoplasms of the vulva.Vulvar and vaginal neoplasms make up a small percentage (3%) of female genital cancers. [1] They can be benign or malignant (vulvar cancer).
Vaginal tumors are neoplasms (tumors) found in the vagina.They can be benign or malignant. [1] [a] A neoplasm is an abnormal growth of tissue that usually forms a tissue mass.[2] [3] [4] Vaginal neoplasms may be solid, cystic or of mixed type.
Vaginal cancer is an extraordinarily rare form of cancer that develops in the tissue of the vagina. [1] Primary vaginal cancer originates from the vaginal tissue – most frequently squamous cell carcinoma, but primary vaginal adenocarcinoma, sarcoma, and melanoma have also been reported [2] – while secondary vaginal cancer involves the metastasis of a cancer that originated in a different ...
The diagnosis is always based on a careful inspection and a targeted biopsy of a visible vulvar lesion. The type and distribution of lesions varies among the two different types of VIN. In the Usual type VIN, seen more frequently in young patients, lesions tend to be multifocal over an otherwise normal vulvar skin.
In Langerhans cell histiocytosis, lesions initially are erythematous, purpuric papules and they then become scaly, crusted and sometimes confluent. In Kawasaki disease, an erythematous, desquamating perineal rash may occur in the second week of symptom onset, almost at the same time as palmoplantar desquamation.
CIN most commonly occurs at the squamocolumnar junction of the cervix, a transitional area between the squamous epithelium of the vagina and the columnar epithelium of the endocervix. [2] It can also occur in vaginal walls and vulvar epithelium. CIN is graded on a 1–3 scale, with 3 being the most abnormal (see classification section below).
Vaginal intraepithelial neoplasia (VAIN) is a condition that describes premalignant histological findings in the vagina characterized by dysplastic changes. [1] The disorder is rare and generally has no symptoms. [2] VAIN can be detected by the presence of abnormal cells in a Papanicolaou test (Pap smear). [2]