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These functions include, brain development, synaptic plasticity and neurodevelopment. Loss of function in AKT can cause microcephaly in humans while inactivation of the pathway can cause hemimegalencephaly. [4] There are also several cancers that have been shown to be linked with mutations in the AKT pathway, including melanoma and lung cancer.
Macrocephaly is a condition in which circumference of the human head is abnormally large. [1] It may be pathological or harmless, and can be a familial genetic characteristic. . People diagnosed with macrocephaly will receive further medical tests to determine whether the syndrome is accompanied by particular disorde
The disease presents with various signs and symptoms affecting different parts of the body. In the head, patients exhibit macrocephaly. This is characterized by megalencephaly, which is the enlargement of the brain leading to an increase in the size of the actual head. [3] In the central nervous system, several symptoms are observed.
The distinctive vascular abnormalities of the skin often fade over time, making the diagnosis challenging in older children with this condition. [citation needed] The brain can be affected in several ways in this syndrome. Some children are born with structural brain anomalies such as cortical dysplasia or polymicrogyria.
Dr. Ahluwalia says that the earliest symptoms of brain cancer depend on the size and location of the brain tumor. “Often, one of the first symptoms is a seizure, which is caused by abnormal ...
Meningiomas are significantly more common in women than in men; they are most common in middle-aged women. Two predisposing factors associated with meningiomas for which at least some evidence exists are exposure to ionizing radiation (cancer treatment of brain tumors) and hormone replacement therapy.
Leptomeningeal cancer is a rare complication of cancer in which the disease spreads from the original tumor site to the meninges surrounding the brain and spinal cord. [1] This leads to an inflammatory response, hence the alternative names neoplastic meningitis (NM), malignant meningitis , or carcinomatous meningitis .
The causes of an enlarged prostate are largely unknown, but there are two risk factors that make it more likely. One is age – you’re more likely to get it if you’re over the age of 50 ...
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