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Patients with hereditary motor and sensory neuropathies are diagnosed through a physical evaluation that looks for muscle atrophy, weakness, and sensory responses. [3] In addition to this, electromyography and motor nerve conduction tests can help clinicians decide what type of motor and sensory neuropathy it is and how severe the disease is.
Nerve conduction studies are beneficial to diagnose certain diseases of the nerves of the body. The test is not invasive, but can be painful due to the electrical shocks administered during the test. The shocks are associated with a low amount of electric current, so they pose minimal risk to the patients.
Hereditary neuropathy with liability to pressure palsy (HNPP) is a peripheral neuropathy, a condition that affects the nerves. [4] Pressure on the nerves can cause tingling sensations, numbness , pain, weakness, muscle atrophy and even paralysis of the affected area.
Diagnostic tests include electromyography (EMG) and nerve conduction studies (NCSs), which assess large myelinated nerve fibers. [33] Testing for small-fiber peripheral neuropathies often relates to the autonomic nervous system function of small thinly- and unmyelinated fibers. These tests include a sweat test and a tilt table test.
To be specific, motor nerve conduction studies of the Median, Ulnar, and peroneal muscles should be performed, as well as sensory nerve conduction studies of the Ulnar and Sural nerves. [ 9 ] In patients with ALS, it has been shown that distal motor latencies and slowing of conduction velocity worsened as the severity of their muscle weakness ...
Motor nerve action potentials and conduction are usually unaffected, but in a subset of cases may have limited dysfunction. [2] Analysis of the cerebrospinal fluid may show increased protein, pleocytosis and oligoclonal bands but this is non-specific. [2] [1] Biopsy of the dorsal nerve root ganglions show a characteristic CD8+ T-cell ...
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