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Levofloxacin and other fluoroquinolones have also been widely used for the treatment of uncomplicated community-acquired respiratory and urinary tract infections, indications for which major medical societies generally recommend the use of older, narrower spectrum drugs to avoid fluoroquinolone resistance development.
Levofloxacin Trovafloxacin. Fluoroquinolones are often used for genitourinary infections [5] and are widely used in the treatment of hospital-acquired infections associated with urinary catheters. In community-acquired infections, they are recommended only when risk factors for multidrug resistance are present or after other antibiotic regimens ...
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
The overall frequency of fluoroquinolone-associated Achilles tendon rupture in patients treated with ciprofloxacin or levofloxacin has been estimated at 17 per 100,000 treatments. [21] [22] Risk is substantially elevated in the elderly and in those with recent exposure to topical or systemic corticosteroid therapy.
Quinolones/Fluoroquinolones Ciprofloxacin: Cipro, Ciproxin, Ciprobay: Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare)
Levofloxacin, which is marketed under the brand name Levaquin in the U.S. and Tavanic in the EU, is often prescribed for pneumonia, urinary tract infections and infections of the abdomen.
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