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Emergence of these self-organized hippocampal events are dependent on interactions between pyramidal cells and different types of the interneurons in this circuit. Pyramidal cells of CA3 and CA1 are important in generating these waves, and they affect the subiculum , parasubiculum , entorhinal cortex , and ultimately neurons of the neocortex. [ 4 ]
The medial septal area projects to a large number of brain regions that show theta modulation, including all parts of the hippocampus as well as the entorhinal cortex, perirhinal cortex, retrosplenial cortex, medial mamillary and supramammillary nuclei of the hypothalamus, anterior nuclei of the thalamus, amygdala, inferior colliculus, and ...
EEG signals picked up in the human (or any large mammalian) cerebral cortex are quite small and diffuse and from the deeper smaller hippocampus they are much more difficult to register. This has meant the study of hippocampal activity has been largely restricted to that of the rat and less often the mouse. [2]
Phase precession in the entorhinal cortex has been hypothesized to arise from an attractor network process, so that two sequential neural representations within a single cycle of the theta oscillation can be temporally linked to each other downstream in the hippocampus, as episodic memories. [13]
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are the components of the hippocampal formation located in the limbic system.
Traditional classification of the frequency bands, that are associated to different functions/states of the brain and consist of delta, theta, alpha, beta and gamma bands. . Due to the limited capabilities of the early experimental/medical setup to record fast frequencies, for historical reason, all oscillations above 30 Hz were considered as high frequency and were difficult to investigate.
The hippocampus is sometimes called the hippocampus proper and just includes the CA subfields (cornu Ammonis 1-4). The hippocampus, dentate gyrus, and other subfields make up the hippocampal formation. The dentate gyrus contains the fascia dentata and the hilus. The CA is differentiated into subfields CA1, CA2, CA3, and CA4. CA4 is often not ...
The entorhinal cortex (EC) is a structure in the brain located in the medial temporal lobe.The EC is composed of six distinct layers. The superficial (outer) layers, which include layers I through III, are mainly input layers that receive signals from other parts of the EC, but also project to hippocampal structures via the perforant path.