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In the 21st century, food addiction are often associated with eating disorders. [5] The term binge eating is defined as eating an unhealthy amount of food while feeling that one's sense of control has been lost. [6] Food addiction initially presents in the form of cravings, which cause a feeling that one cannot cope without the food in question ...
Physiological antagonism describes the behavior of a substance that produces effects counteracting those of another substance (a result similar to that produced by an antagonist blocking the action of an agonist at the same receptor) using a mechanism that does not involve binding to the same receptor.
The mesolimbic pathway and a specific set of the pathway's output neurons (e.g. D1-type medium spiny neurons within the nucleus accumbens) play a central role in the neurobiology of addiction. [20] [21] [22] Drug addiction is an illness caused by habitual substance use that induces chemical changes in the brain's circuitry. [23]
Gastrointestinal physiology is the branch of human physiology that addresses the physical function of the gastrointestinal (GI) tract.The function of the GI tract is to process ingested food by mechanical and chemical means, extract nutrients and excrete waste products.
Drug delivery to the brain is the process of passing therapeutically active molecules across the blood–brain barrier into the brain.This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the blood–brain barrier.
An addiction to ultraprocessed foods can highjack a young brain’s reward circuitry, putting the primitive “reptilian brain,” or amygdala, in charge — thus bypassing the prefrontal cortex ...
Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein–coupled receptors. [5]
Addiction is believed to be a disorder of experience-dependent brain plasticity. [35] The reinforcing effects of nicotine play a significant role in the beginning and continuing use of the drug. [36] First-time nicotine users develop a dependence about 32% of the time. [37] Chronic nicotine use involves both psychological and physical ...