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Dexmedetomidine, sold under the brand name Precedex among others, is a medication used for sedation. [4] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. [ 10 ] [ 11 ] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar disorder . [ 5 ]
The equation used to calculate this minimal work was derived from the work of Otis et.al. [14] and published and discussed in Grodins and Yamashiro as early as 1977. [15] In the ASV mode, every breath is synchronized with patient effort if such an effort exists, and otherwise, full mechanical ventilation is provided to the patient.
Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.
Arkansas said it ran out of ICU beds for COVID-19 patients for the first time since the pandemic began. Nearly 80% of the country's ICU beds — or about 68,000 — were in use Thursday, according ...
α 2 agonist: inhibits adenylyl cyclase activity, reduces brainstem vasomotor center-mediated CNS activation; used as antihypertensive, sedative & treatment of opiate dependence and alcohol withdrawal symptoms). Selected examples are: Brimonidine; Clonidine (mixed alpha2-adrenergic and imidazoline-I1 receptor agonist) Dexmedetomidine; Fadolmidine
They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.
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The Epimed Monitor ICU Database®: a cloud-based national registry for adult intensive care unit patients in Brazil. Zampieri FG, Soares M, Borges LP, Salluh JIF, Ranzani OT.Rev Bras Ter Intensiva. 2017 Oct-Dec;29(4):418-426. doi: 10.5935/0103-507X.20170062.