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  2. List of polymorphisms - Wikipedia

    en.wikipedia.org/wiki/List_of_polymorphisms

    All the flies look alike whatever inversions they carry: this is an example of a cryptic polymorphism. Accordingly, Dobzhansky favoured the idea that the morphs became fixed in the population by means of Sewall Wright's drift. [54] However, evidence rapidly accumulated to show that natural selection was responsible: Drosophila polytene ...

  3. Polymorphism (biology) - Wikipedia

    en.wikipedia.org/wiki/Polymorphism_(biology)

    In biology, polymorphism [1] is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species. To be classified as such, morphs must occupy the same habitat at the same time and belong to a panmictic population (one with random mating).

  4. Gene polymorphism - Wikipedia

    en.wikipedia.org/wiki/Gene_polymorphism

    Polymorphisms can be identified in the laboratory using a variety of methods. Many methods employ PCR to amplify the sequence of a gene. Once amplified, polymorphisms and mutations in the sequence can be detected by DNA sequencing, either directly or after screening for variation with a method such as single strand conformation polymorphism analysis.

  5. SNP array - Wikipedia

    en.wikipedia.org/wiki/SNP_array

    In molecular biology, SNP array is a type of DNA microarray which is used to detect polymorphisms within a population. A single nucleotide polymorphism (SNP), a variation at a single site in DNA, is the most frequent type of variation in the genome.

  6. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    Polymorphism can be maintained by selection favoring the heterozygote, and this mechanism is used to explain the occurrence of some kinds of genetic variability. A common example is the case where the heterozygote conveys both advantages and disadvantages, while both homozygotes convey a disadvantage.

  7. Single-nucleotide polymorphism - Wikipedia

    en.wikipedia.org/wiki/Single-nucleotide_polymorphism

    In genetics and bioinformatics, a single-nucleotide polymorphism (SNP / s n ɪ p /; plural SNPs / s n ɪ p s /) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.g. 1% or more), [ 1 ...

  8. Chromosomal polymorphism - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_polymorphism

    Polymorphism is a general concept in biology where more than one version of a trait is present in a population. In some cases of differing counts, the difference in chromosome counts is the result of a single chromosome undergoing fission , where it splits into two smaller chromosomes, or two undergoing fusion, where two chromosomes join to ...

  9. Population genetics - Wikipedia

    en.wikipedia.org/wiki/Population_genetics

    For example, in the simplest case of a single locus with two alleles denoted A and a at frequencies p and q, random mating predicts freq(AA) = p 2 for the AA homozygotes, freq(aa) = q 2 for the aa homozygotes, and freq(Aa) = 2pq for the heterozygotes. In the absence of population structure, Hardy-Weinberg proportions are reached within 1–2 ...