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Aseptic processing was derived from Olin Ball's heat-cool-fill (HCF) machine that was developed in 1927. [5] While HCF was successful in improving the sensory quality of the processed chocolate milk as compared to canned product, the use of the equipment was hindered by its cost, maintenance, and inflexibility to process various container sizes, rendering the machine a failure.
The most common EO processing method is the gas chamber. To benefit from economies of scale , EO has traditionally been delivered by filling a large chamber with a combination of gaseous EO, either as pure EO, or with other gases used as diluents; diluents include chlorofluorocarbons ( CFCs ), hydrochlorofluorocarbons (HCFCs), and carbon dioxide .
In limited cases, they can also be used to protect a sterile product, when supplied with ISO 5 unidirectional air. However, in some notable cases, gloveboxes used for aseptic processing have provided no more sterile product protection than the traditional laminar air flow hood (LAF) design of the 1960s. In these cases, the glove boxes were ...
Aseptic processing involves maintaining a sterile environment to prevent the introduction of contaminants during the manufacturing of products, such as sterile injectable medications and sterile medical equipment. This requires stringent control over personnel behavior, equipment sterilization, and the cleanroom environment. [16]
Sterile dental instruments from hospital central supply (barcoded label indicating sterilization date, expiry date and contents). The central sterile services department (CSSD), also called sterile processing department (SPD), sterile processing, central supply department (CSD), or central supply, is an integrated place in hospitals and other health care facilities that performs sterilization ...
[3] [4] BFS is an advanced aseptic processing technology that is typically used for filling and packaging of certain sterile liquid formulations like liquid ophthalmics, inhalational anesthetics, or lavaging agents, but can also be used for injectables, [1] parenteral medicines, [5] and several other liquid or semiliquid medications, [6] with ...
Basic aseptic procedures includes hand washing, donning protective gloves, masks and gowns, and sterilizing equipment and linens. [12] Medical aseptic techniques also includes curbing the spread of infectious diseases through quarantine, specifically isolation procedures based on the mode of disease transmission. [ 12 ]
Philip E. Nelson (born 1934 [1]) is an American food scientist who is best known for his work in bulk aseptic processing and packaging of food and the use of chlorine dioxide gas and hydrogen peroxide liquid to commercially sterilize food products and food contact surfaces.