Search results
Results from the WOW.Com Content Network
Fortrea primate-testing lab, Vienna, Virginia, 2004–05. Most of the NHPs used are one of three species of macaques, accounting for 79% of all primates used in research in the UK, and 63% of all federally funded research grants for projects using primates in the U.S. [25] Lesser numbers of marmosets, tamarins, spider monkeys, owl monkeys, vervet monkeys, squirrel monkeys, and baboons are used ...
An animal model (short for animal disease model) is a living, non-human, often genetic-engineered animal used during the research and investigation of human disease, for the purpose of better understanding the disease process without the risk of harming a human. Although biological activity in an animal model does not ensure an effect in humans ...
For instance, behavioral analogues of anxiety or pain in laboratory animals can be used to screen and test new drugs for the treatment of these conditions in humans. A 2000 study found that animal models concorded (coincided on true positives and false negatives) with human toxicity in 71% of cases, with 63% for nonrodents alone and 43% for ...
Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...
One of Pavlov’s dogs with a saliva-catch container and tube surgically implanted in its muzzle, Pavlov Museum, 2005. The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. [1]
In 2010, a new EU directive was published on the protection of animals used for scientific purposes, repealing the old directive 86/609/EEC on January 1, 2013, with the exception of Article 13 (statistical information on the use of animals in experiments) which has been repealed on May 10, 2013. [19]
Experiments on vertebrate animals in the European Union are since January 1, 2013. [1] [2] subject to Directive 2010/63/EU on the protection of animals used for scientific purposes, which was finalized in November 2010 and updated and replaced the Directive 86/609/EEC on the protection of Animals used for Experimental and other scientific purposes, adopted in 1986. [3]
Opioids are commonly used in both human and animal medicine, as they bind to different receptors in the brain and spinal cord to produce varying effects. [16] These drugs, including Oxymorphone, Morphine, Fentanyl, Methadone, Buprenorphine, and Butorphanol, have been highly used in veterinary anesthesia due to their sedative and analgesic ...