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Physician Assistant Jeanie Boulet leaves to care for her HIV-positive child. Lucy Knight and John Carter are attacked and stabbed by a psychotic patient. The ER staff work to save Carter and Lucy. Despite everyone's best efforts, they are unable to save Lucy who succumbs to her wounds and dies.
Lucy's memorial service takes place in the episode "Be Patient", although it is not seen on-screen and is apparently only attended by Jing-Mei Chen, who is there more as a representative of the ER than as a friend of Lucy's. That same day, Lucy's mother, Barbara Knight, arrives to clear out her locker.
Lucy Knight (Kellie Martin) and Carter develop a liking for each other. Carter was jealous when Lucy started going out with Dr. Dale Edson (Matthew Glave). Carter and Lucy kiss only once as he decides to break things off owing to her being a medical student. They continued to be friends, until her death in Season 6.
Jeanie is not critically injured from the previous episode's crash but gets other bad medical news. Mobalage's wife is having doubts about her husband's surgery and shares a horrifying secret with Hathaway. Carter and Lucy decide not to pursue a relationship despite the kiss shared in a previous episode. Mobalage's wife is brutally stabbed.
In the tenth season, Romano gets a robotic arm. In the episode "Freefall," he is killed when a helicopter falls off the hospital roof and crushes him. Prior to his death, he had intended to lodge a complaint against Dr. Greg Pratt and caught Dr. Archie Morris smoking pot. He leaves a large amount of money to the hospital in his will, which ...
Abby fills in as Carter's date for a Carter family function and sees her ex-husband there, later making sure to ruin his evening. Malucci treats a gay man who wants to contract HIV from his positive partner. Greene continues an abrupt personality change in the wake of his surgery. Weaver makes an appointment for a competency review for Greene.
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Schizophrenic patient who in a psychotic break stabbed both Dr. John Carter and Lucy Knight, the wounds leaving Carter injured and with life-long kidney problems and eventually resulted in Lucy's death 2000, 2002 James Cromwell: Bishop Lionel Stewart Catholic bishop who helped Dr. Luka Kovač with his guilt about the death of his family 2001