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Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. [5] Two forms of this protein have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.
Two different classes of thymidine kinases have been identified [8] [9] and are included in this super family: one family groups together thymidine kinase from herpesvirus as well as cellular thymidylate kinases, the second family groups TK from various sources that include, vertebrates, bacteria, the bacteriophage T4, poxviruses, African swine fever virus (ASFV) and Fish lymphocystis disease ...
An integral, or intrinsic, membrane protein (IMP) [1] is a type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins can be classified as IMPs, but not all IMPs are transmembrane proteins. [2] IMPs comprise a significant fraction of the proteins encoded in an organism's genome. [3]
Intramembrane proteases (IMPs), also known as intramembrane-cleaving proteases (I-CLiPs), are enzymes that have the property of cleaving transmembrane domains of integral membrane proteins. [ 1 ] [ 2 ] [ 3 ] All known intramembrane proteases are themselves integral membrane proteins with multiple transmembrane domains, and they have their ...
In this case hypoxanthine-guanine phosphoribosyltransferase (HGPRT) reacts hypoxanthine absorbed from the medium with PRPP, liberating pyrophosphate, to produce IMP by a salvage pathway. Therefore, the use of HAT medium for cell culture is a form of artificial selection for cells containing working TK and HGPRT. Many useful refinements to the ...
An IMP requires the connection to a host computer via a special bit-serial interface, defined in BBN Report 1822. The IMP software and the ARPA network communications protocol running on the IMPs was discussed in RFC 1, [6] the first of a series of standardization documents published by what later became the Internet Engineering Task Force (IETF).
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene. HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. This ...
The OMA Instant Messaging and Presence Service (IMPS) is an Open Mobile Alliance enabler for Instant Messaging and Presence. The Wireless Village consortium developed the first cut of the specifications. After Wireless Village was merged with OMA, its specs became OMA IMPS 1.0