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Tetralogy of Fallot (TOF), formerly known as Steno-Fallot tetralogy, [9] is a congenital heart defect characterized by four specific cardiac defects. [4] Classically, the four defects are: [ 4 ] pulmonary stenosis , which is narrowing of the exit from the right ventricle;
Digital clubbing with cyanotic nail beds in an adult with tetralogy of Fallot. Signs and symptoms are related to type and severity of the heart defect. Symptoms frequently present early in life, but it is possible for some CHDs to go undetected throughout life. [15]
Tetralogy of Fallot is actually the most common cause of cyanotic congenital heart defects, accounting for about 50-70%, as well as about 10% of all congenital heart defects in general. Now, it’s not quite clear why some babies develop TOF but it is associated with chromosome 22 deletions and DiGeorge syndrome.
Eileen Saxon, sometimes referred to as "The Blue Baby", was the first patient that received the operation now known as Blalock–Thomas–Taussig shunt.. She had a condition called Tetralogy of Fallot, one of the primary congenital defects that lead to blue baby syndrome.
Eisenmenger syndrome or Eisenmenger's syndrome is defined as the process in which a long-standing left-to-right cardiac shunt caused by a congenital heart defect (typically by a ventricular septal defect, atrial septal defect, or less commonly, patent ductus arteriosus) causes pulmonary hypertension [1] [2] and eventual reversal of the shunt into a cyanotic right-to-left shunt.
Life expectancy [163] increases with age already achieved. The table above gives the life expectancy at birth among 13th-century English nobles as 30–33, but having surviving to the age of 21, a male member of the English aristocracy could expect to live: 1200–1300: to age 64; 1300–1400: to age 45 (because of the bubonic plague)
Trilogy of Fallot is a combination of three congenital heart defects: pulmonary stenosis, right ventricular hypertrophy, and an atrial septal defect. [ 1 ] The first two of these are also found in the more common tetralogy of Fallot .
All infants with TGA will need surgery to correct the defect. Life expectancy is only a few months if corrective surgery is not performed. [citation needed] Before surgery: For newborns with transposition, prostaglandins can be given to keep the ductus arteriosus open which allows for the mixing of the otherwise isolated pulmonary and systemic ...