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Contrary to popular belief, nicotine itself does not cause cancer in humans, [40] ... The initial symptoms of a nicotine overdose typically include nausea, ...
The onset of these symptoms is very fast, nicotine's half-life being only two hours. [154] The psychological dependence may linger for months or even many years. Unlike some recreational drugs, nicotine does not measurably alter a smoker's motor skills, judgement, or language abilities while under the influence of the drug. Nicotine withdrawal ...
Nicotine is an agonist at nicotinic acetylcholine receptor which are present in the central and autonomic nervous systems, and the neuromuscular junction. At low doses nicotine causes stimulatory effects on these receptors, however, higher doses or more sustained exposures can cause inhibitory effects leading to neuromuscular blockade. [4] [30]
Nicotine itself, however, is addictive but not otherwise very harmful, as shown by the long history of people safely using nicotine replacement therapy products (e.g., nicotine gum, nicotine patch). [13] Nicotine increases heart rate and blood pressure and has a range of local irritant effects but does not cause cancer. [14]
This does not, however, eliminate any harm to health caused by the nicotine itself. Current research focuses on possible long-term side effects of nicotine on blood pressure, hypertension, and possible risk of pancreatic cancer due to tobacco-specific nitrosamines (TSNAs).
The FDA recently announced a plan that would force tobacco companies to dramatically decrease levels of the highly-addictive substance in cigarettes.
Nicotine pouch ads are making the rounds, but read this before you try them. Experts explain how safe nicotine pouches are compared to cigarettes and e-cigarettes. Nicotine pouch ads are making ...
Smoking tobacco causes various types and subtypes of cancers [94] (particularly lung cancer, cancers of the oropharynx, [95] larynx, [95] and mouth, [95] esophageal and pancreatic cancer). [18] Using tobacco, especially together with alcohol , is a major risk factor for head and neck cancer . 72% of head and neck cancer cases are caused by ...