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2. Yeast artificial chromosome - Wikipedia

   en.wikipedia.org/wiki/Yeast_artificial_chromosome

   Yeast artificial chromosomes (YACs) are genetically engineered chromosomes derived from the DNA of the yeast, Saccharomyces cerevisiae, which is then ligated into a bacterial plasmid. By inserting large fragments of DNA, from 100–1000 kb, the inserted sequences can be cloned and physically mapped using a process called chromosome walking .

3. Saccharomyces cerevisiae - Wikipedia

   en.wikipedia.org/wiki/Saccharomyces_cerevisiae

   Saccharomyces cerevisiae (/ ˌ s ɛr ə ˈ v ɪ s i. iː /) (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungal microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been originally isolated from the skin of grapes.

4. Artificial chromosome - Wikipedia

   en.wikipedia.org/wiki/Artificial_chromosome

   Artificial chromosome may refer to: Yeast artificial chromosome; Bacterial artificial chromosome; ... This page was last edited on 18 February 2021, at 04:48 (UTC).

5. Genomic library - Wikipedia

   en.wikipedia.org/wiki/Genomic_library

   Yeast artificial chromosomes (YACs) are linear DNA molecules containing the necessary features of an authentic yeast chromosome, including telomeres, a centromere, and an origin of replication. Large inserts of DNA can be ligated into the middle of the YAC so that there is an “arm” of the YAC on either side of the insert.

6. Vector (molecular biology) - Wikipedia

   en.wikipedia.org/wiki/Vector_(molecular_biology)

   Artificial chromosomes are manufactured chromosomes in the context of yeast artificial chromosomes (YACs), bacterial artificial chromosomes (BACs), or human artificial chromosomes (HACs). An artificial chromosome can carry a much larger DNA fragment than other vectors. [9] YACs and BACs can carry a DNA fragment up to 300,000 nucleotides long.

7. Yeast artificial chromosomes - Wikipedia

   en.wikipedia.org/?title=Yeast_artificial...

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8. Human artificial chromosome - Wikipedia

   en.wikipedia.org/wiki/Human_artificial_chromosome

   A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6–10 megabases (Mb) in size instead of 50–250 Mb for natural chromosomes, and able to carry new genes introduced by human researchers.

9. Artificial gene synthesis - Wikipedia

   en.wikipedia.org/wiki/Artificial_gene_synthesis

   The first synthetic yeast chromosome was synthesised in 2014, and entire functional bacterial chromosomes have also been synthesised. [5] In addition, artificial gene synthesis could in the future make use of novel nucleobase pairs (unnatural base pairs). [6] [7] [8]