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The initial case in human outbreaks of Nipah virus has always been zoonotic [8] from exposure to contaminated secretions or tissues of infected bats or pigs. Subsequent human-to-human transmission of Nipah virus occurs via close contact with NiV-infected persons or exposure to NiV-infected body fluids (e.g., blood, urine, nasal secretions). [1]
The Nipah virus structural model, constructed at an atomic resolution, depicts a particle with a diameter of 90 nm, adorned with spikes. This model affords a glimpse into the virus's interior. The Nipah virus is known for its high mortality rate and is viewed as a potential candidate for the next pandemic.
A zoonosis (/ z oʊ ˈ ɒ n ə s ɪ s, ˌ z oʊ ə ˈ n oʊ s ɪ s / ⓘ; [1] plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite, or prion) that can jump from a non-human vertebrate to a human.
The virus is often transmitted by bats. For premium support please call: 800-290-4726 more ways to reach us
The virus firstly struck pig-farms in the suburb of Ipoh in Perak with the occurrence of respiratory illness and encephalitis among the pigs, where it was initially believed to have been caused by Japanese encephalitis (JE), due to four serum samples from 28 infected humans in the area which tested positive for JE-specific Immunoglobulin M (IgM) which is also confirmed by the findings of the ...
In its sixth outbreak in the country since 2001 this year, the virus, known for its 70% mortality rate, has claimed two lives out of the six who were infected in a span of few days in September ...
Nipah virus (NiV) replication cycle As all mononegaviral genomes, Hendra virus and Nipah virus genomes are non-segmented, single-stranded negative-sense RNA. Both genomes are 18.2 kb in length and contain six genes corresponding to six structural proteins.
Hendra virus and Nipah virus in the genus Henipavirus have emerged in humans and livestock in Australia and Southeast Asia. Both viruses are contagious , highly virulent , and capable of infecting a number of mammalian species and causing potentially fatal disease.