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The trichothecene mycotoxins are toxic to humans, other mammals, birds, fish, a variety of invertebrates, plants, and eukaryotic cells. [21] The specific toxicity varies depending on the particular toxin and animal species, however the route of administration plays a significantly higher role in determining lethality.
Zearalenone is a white crystalline solid, with molecular formula C 18 H 22 O 5 and 318.364 g/mol molecular weight. It is a resorcyclic acid lactone.It exhibits blue-green fluorescence when excited by long wavelength ultraviolet (UV) light (360 nm) and a more intense green fluorescence when excited with short wavelength UV light (260 nm). [4]
Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. [7] [8] It is also used off-label to control sarcoptic mange and demodectic mange. [8] Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin ...
There were outbreaks of dog food containing aflatoxin in North America in late 2005 and early 2006, [38] and again in late 2011. [39] Mycotoxins in animal fodder, particularly silage, can decrease the performance of farm animals and potentially kill them. [40] [4] Several mycotoxins reduce milk yield when ingested by dairy cattle. [40]
Family Dollar recalls more than 400 over-the-counter products. Here’s what to know. GoodSense, lemon and cherry flavors. A deconstructed box of Good Sense Magnesium Citrate laxative, cherry ...
T-2 mycotoxin is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and other animals. The clinical condition it causes is alimentary toxic aleukia and a host of symptoms related to organs as diverse as the skin, airway, and stomach.
The hybrid toxin-targeting molecule would then bind only the target cells, and deliver the toxin, killing them. In one study, a toxin (pokeweed antiviral protein) was conjugated to GnRH to target the GnRH receptors on the pituitary gonadotrophs. Treatment of dogs showed a decrease in testosterone, which however was not permanent. [27]
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