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A total nephrectomy is the removal of at least the entire kidney, whereas a 'radical nephrectomy' also includes at least some perinephric fat, possibly including Gerota's fascia, and usually also the ipsilateral adrenal gland. [10] For some illnesses, there are alternatives today that do not require the extraction of a kidney.
This facilitates milking of the tumor down below the major hepatic veins by the surgeon's fingers, bypassing the need for a thoracoabdominal incision or cardiopulmonary bypass. [78] In cases of known metastases, surgical resection of the kidney ("cytoreductive nephrectomy") may improve survival, [79] as well as resection of a solitary ...
Radical surgery, also called radical dissection, is surgery that is more extensive than "conservative" surgery. In surgical oncology , radical surgery is surgery intended to remove both a tumor and any metastases thereof, for diagnostic and/or treatment purposes. [ 1 ]
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Major depression is often associated with biomarkers indicative of inflammatory responses, with interleukin-6, interleukin-1, interleukin-2 receptor, tumor necrosis factor alpha, C-reactive protein, and monocyte chemotactic protein-1 all being found to be elevated in those with depression.
Watson and Clark (1991) proposed the Tripartite Model of Anxiety and Depression to help explain the comorbidity between anxious and depressive symptoms and disorders. [1] This model divides the symptoms of anxiety and depression into three groups: negative affect, positive affect and physiological hyperarousal.
The triad forms part of his cognitive theory of depression [4] and the concept is used as part of CBT, particularly in Beck's "Treatment of Negative Automatic Thoughts" (TNAT) approach. The triad involves "automatic, spontaneous and seemingly uncontrollable negative thoughts" about the self , the world or environment , and the future.
Bilateral cingulotomy is a form of psychosurgery, introduced in 1948 as an alternative to lobotomy.Today, it is mainly used in the treatment of depression [1] and obsessive-compulsive disorder.