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The US Food and Drug Administration approved the first nasal spray epinephrine drug for severe allergic reactions known as anaphylaxis, providing a needle-free alternative to EpiPens and similar ...
The first-ever needle-free alternative to the EpiPen and similar epinephrine autoinjectors has been approved by the Food and Drug Administration to treat anaphylaxis.. Neffy, a nasal spray that ...
The nasal-spray Neffy was rejected by the FDA. The epinephrine nasal spray would've been the first needle-free alternative to EpiPens, but the FDA said additional research was needed.
Historically, pen needles were manufactured in lengths up to 12.7mm. Over time, pen needles designed for insulin pens have become shorter, and a 4mm long needle is considered sufficient for most people to administer subcutaneously correctly. [23] In 1989, an injector pen form of human growth hormone was licensed in New Zealand. [28]
A needle and syringe programme (NSP), also known as needle exchange program (NEP), is a social service that allows injection drug users (IDUs) to obtain clean and unused hypodermic needles and associated paraphernalia at little or no cost.
A newer variant of the autoinjector is the gas jet autoinjector, which contains a cylinder of pressurized gas and propels a fine jet of liquid through the skin without using a needle. This has the advantage that patients who fear needles are more accepting of using these devices.
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The first modern epinephrine autoinjector, the EpiPen, was invented in the mid-1970s at Survival Technology in Bethesda, Maryland, US by Sheldon Kaplan [11] [12] and was first approved for marketing by the FDA in 1987. [13] One of the people who helped in making the EpiPen was Richard B. Toren.