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  2. Transketolase - Wikipedia

    en.wikipedia.org/wiki/Transketolase

    Transketolase (abbreviated as TK) is an enzyme that, in humans, is encoded by the TKT gene. [1] It participates in both the pentose phosphate pathway in all organisms and the Calvin cycle of photosynthesis. Transketolase catalyzes two important reactions, which operate in opposite directions in these two pathways.

  3. Physiologically based pharmacokinetic modelling - Wikipedia

    en.wikipedia.org/wiki/Physiologically_based...

    The model equations follow the principles of mass transport, fluid dynamics, and biochemistry in order to simulate the fate of a substance in the body. [9] Compartments are usually defined by grouping organs or tissues with similar blood perfusion rate and lipid content (i.e. organs for which chemicals' concentration vs. time profiles will be similar).

  4. Formaldehyde transketolase - Wikipedia

    en.wikipedia.org/wiki/Formaldehyde_transketolase

    In enzymology, a formaldehyde transketolase (EC 2.2.1.3) is an enzyme that catalyzes the chemical reaction D-xylulose 5-phosphate + formaldehyde ⇌ {\displaystyle \rightleftharpoons } glyceraldehyde 3-phosphate + glycerone

  5. Thiamine pyrophosphate - Wikipedia

    en.wikipedia.org/wiki/Thiamine_pyrophosphate

    In what is essentially the reverse of step two, the electrons push back in the opposite direction forming a new bond between the substrate carbon and another atom. (In the case of the decarboxylases, this creates a new carbon-hydrogen bond. In the case of transketolase, this attacks a new substrate molecule to form a new carbon-carbon bond.)

  6. Transferase - Wikipedia

    en.wikipedia.org/wiki/Transferase

    transketolase and transaldolase: aldehyde or ketone groups EC 2.3: acyltransferase: acyl groups or groups that become alkyl groups during transfer EC 2.4: glycosyltransferase, hexosyltransferase, and pentosyltransferase: glycosyl groups, as well as hexoses and pentoses: EC 2.5: riboflavin synthase and chlorophyll synthase: alkyl or aryl groups ...

  7. Ribose 5-phosphate - Wikipedia

    en.wikipedia.org/wiki/Ribose_5-phosphate

    Ribose 5-phosphate (R5P) is both a product and an intermediate of the pentose phosphate pathway.The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate.

  8. Xylulose 5-phosphate - Wikipedia

    en.wikipedia.org/wiki/Xylulose_5-phosphate

    In the non-oxidative branch of the pentose phosphate pathway, xylulose-5-phosphate acts as a donor of two-carbon ketone groups in transketolase reactions. [ 2 ] Xylulose-5-phosphate also plays a crucial role in the regulation of glycolysis through its interaction with the bifunctional enzyme PFK2/FBPase2.

  9. Metabolic network modelling - Wikipedia

    en.wikipedia.org/wiki/Metabolic_network_modelling

    Metabolic network model for Escherichia coli. Metabolic network modelling, also known as metabolic network reconstruction or metabolic pathway analysis, allows for an in-depth insight into the molecular mechanisms of a particular organism. In particular, these models correlate the genome with molecular physiology. [1]