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Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer. [2] Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion .
It is administered by intravenous injection and is often prescribed in combination with radiotherapy or other chemotherapeutic regimens such as irinotecan. Since EGFR plays an essential role in maintaining skin integrity, one serious side effect of Cetuximab therapy is skin problems such as acne-like rash , skin drying and cracking due to the ...
Intravesical drug delivery through a urinary catheter. Intravesical drug delivery is the delivery of medications directly into the bladder by urinary catheter.This method of drug delivery is used to directly target diseases of the bladder such as interstitial cystitis and bladder cancer, but currently faces obstacles such as low drug retention time due to washing out with urine and issues with ...
A urine test is any medical test performed on a urine specimen. The analysis of urine is a valuable diagnostic tool because its composition reflects the functioning of many body systems, particularly the kidneys and urinary system , and specimens are easy to obtain. [ 1 ]
The bladder is an organ that stores urine until it is released from the body. Several conditions can affect the bladder including urinary tract infections, bladder stones, bladder cancer, overactive bladder, cystitis, interstitial cystitis, abscess, fistula, and urinary incontinence. [4] [5] [1]
Panitumumab was initially approved on September 27, 2006, for EGFR-expressing, metastatic CRC with disease progression on or following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing regimens, based on the results of a study which showed clinical benefit in metastatic colorectal cancer patients. [13]
In radiology and urology, a cystography (also known as cystogram) is a procedure used to visualise the urinary bladder. Using a urinary catheter, radiocontrast is instilled in the bladder, and X-ray imaging is performed. Cystography can be used to evaluate bladder cancer, vesicoureteral reflux, bladder polyps, and hydronephrosis.
Bladder cancer prognosis varies based on how widespread the cancer is at the time of diagnosis. For those with tumors confined to the innermost layer of the bladder (stage 0 disease), 96% are still alive five years from diagnosis. Those whose tumors have spread to nearby lymph nodes (stage 3 disease) have worse prognoses; 36% survive at least ...