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Labetalol is a medication used to treat high blood pressure and in long term management of angina. [ 4 ] [ 5 ] This includes essential hypertension , hypertensive emergencies , and hypertension of pregnancy . [ 5 ]
They are one of the three major causes of death in pregnancy (16%) along with post partum bleeding (13%) and puerperal infections (2%). [6] Hypertensive disorders during pregnancy, such as gestational hypertension, preeclampsia, and eclampsia, are a major contributor to maternal and fetal illness and death on a worldwide scale.
When it occurs in pregnancy it is known as eclampsia. [2] The diagnosis requires ruling out other possible causes. [1] The condition is generally treated with medications to relatively rapidly lower the blood pressure. [2] [3] This may be done with labetalol or sodium nitroprusside given by injection into a vein. [2]
Aug. 21—HUNTINGTON, W.Va. — The Marshall University Joan C. Edwards School of Medicine is now enrolling participants in a randomized controlled trial comparing the outcomes of treatment and ...
Although α-methyldopa is generally regarded as a first-line agent, labetalol and metoprolol are also acceptable. Atenolol has been associated with intrauterine growth retardation, as well as decreased placental growth and weight when prescribed during pregnancy. ACEis and ARBs are contraindicated in women who are or who intend to become pregnant.
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Hydralazine is often used to treat hypertension in pregnancy, though, with either labetalol and/or methyldopa. [11] Hydralazine is commonly used in combination with isosorbide dinitrate for the treatment of congestive heart failure in black populations. This preparation, isosorbide dinitrate/hydralazine, was the first race-based prescription ...
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