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Testicular atrophy is a medical condition in which one or both testicles (or "testes") diminish in size and may be accompanied by reduced testicular function. Testicular atrophy is not related to the temporary shrinkage of the surrounding scrotum , which might occur in response to cold temperature.
In some cases, testosterone replacement therapy can also worsen symptoms associated with low T, such as gynecomastia, sleep apnea, and testicular shrinkage. Additionally, TRT may be unsafe if you ...
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
Hypogonadism means diminished functional activity of the gonads—the testicles or the ovaries—that may result in diminished production of sex hormones.Low androgen (e.g., testosterone) levels are referred to as hypoandrogenism and low estrogen (e.g., estradiol) as hypoestrogenism.
Medicare may cover testosterone replacement therapy (TRT) to treat symptomatic hypogonadism, delayed puberty, and gender dysphoria.
However, in a study of transgender men who are using TRT as part of their medical transition, 5 to 17 percent were found to develop some hair loss in their first year of TRT.
This manifests in testicular atrophy, inhibition of the production of sperm, sexual function and infertility. [ 106 ] [ 107 ] [ 108 ] A short (1–2 months) use of androgenic-anabolic steroids by men followed by a course of testosterone-boosting therapy (e.g. clomifene and human chorionic gonadotropin ) usually results in return to normal ...
One study concluded that long-term testosterone replacement therapy (TRT) in middle-aged men with late-onset hypogonadism (LOH) and metabolic syndrome (MS) led to a significant increase in both vertebral and femoral bone mineral density (BMD) after 36 months of treatment, as measured by dual-energy x-ray absorptiometry. The TRT treatment was ...