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Hyperthermic intraperitoneal chemotherapy (HIPEC) is a type of hyperthermia therapy used in combination with surgery in the treatment of advanced abdominal cancers. [1] In this procedure, warmed anti-cancer medications are infused and circulated in the peritoneal cavity (abdomen) for a short period of time.
Ovarian cancer is highly treatable with surgery for almost all cases with well-differentiated stage-1 tumour. [4] [33] Higher tumour grades may benefit from adjuvant treatment such as platinum-based chemotherapy. [4] [33] Optimal debulking is used to treat cases where cancer has spread to become macroscopically advanced.
Debulking is the reduction of as much of the bulk of a tumour without the intention of a complete eradication. It is usually achieved by surgical removal. [1] [2] When performed for curative intent, it is a different procedure, which is called surgical debulking of tumors is known as cytoreduction or cytoreductive surgery [3] (CRS); "cytoreduction" refers to reducing the number of tumor cells.
Cytoreductive surgery (CRS) is a surgical procedure that aims to reduce the amount of cancer cells in the abdominal cavity for patients with tumors that have spread intraabdominally (peritoneal carcinomatosis). It is often used to treat ovarian cancer but can also be used for other abdominal malignancies.
Ovarian cancer is a cancer that forms in or on an ovary. [1] [2] It results in abnormal cells that have the ability to invade or spread to other parts of the body. [3] When this process begins, there may be no or only vague symptoms. [4] Symptoms become more noticeable as the cancer progresses.
The most common types of cancer discovered through abdominal surgery are gastrointestinal, such as colon or stomach, or genital or urinary, Dr. Ben Ho Park, director of precision oncology at ...
People having ovarian cancer surgery are typically hospitalized afterwards for 3–4 days and spend around a month recovering at home. [108] Surgery outcomes are best at hospitals that do a large number of ovarian cancer surgeries. [29] It is unclear if laparoscopy or laparotomy is better or worse for FIGO stage I ovarian cancer. [109]
Cytoreductive "debulking" surgery may be performed prior to chemotherapy treatment in order to decrease the physical mass of the tumour and thus reduce the number of chemotherapy cycles needed. [39] The typical advanced presentation as well as extra-ovarian spread seen in HGSC can require aggressive debulking procedures. [ 51 ]