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Faster or stronger binding is represented by a higher affinity, or equivalently a lower dissociation constant. The EC 50 should not be confused with the affinity constant, K d. While the former reflects the drug concentration needed for a level of tissue response, the latter reflects the drug concentration needed for an amount of receptor binding.
The parameters of the dose response curve reflect measures of potency (such as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response). A commonly used dose–response curve is the EC 50 curve, the half maximal effective concentration, where the EC 50 point is defined as the inflection point of the curve.
An air speed record is the highest airspeed attained by an aircraft of a particular class. The rules for all official aviation records are defined by Fédération Aéronautique Internationale (FAI), [ 1 ] which also ratifies any claims.
Seoul (Reuters) -Investigators found bird feathers and blood in both engines of the Jeju Air jet that crashed in South Korea last month, killing 179 people, a person familiar with the probe told ...
Upwind: the rotor harvests power from the oncoming air and drives the wheels, as would a wind turbine. Downwind: when the vehicle is traveling faster than the windspeed, the ground is the fastest-moving medium relative to the vehicle, so the wheels harvest the power and impart it to the rotor, which propels the vehicle. [8]
In the deadliest U.S. air disaster in more than 20 years, a U.S. Army helicopter and an American Airlines passenger jet collided on Wednesday night near Ronald Reagan Washington National Airport ...
Alternate between bursts of more challenging (i.e., higher intensity, faster speed, or steeper incline) work and recovery (i.e., lower intensity, slower speed, and zero incline) at a two-to-one ratio.
Blast waves cause damage by a combination of the significant compression of the air in front of the wave (forming a shock front) and the subsequent wind that follows. [15] A blast wave travels faster than the speed of sound, and the passage of the shock wave usually lasts only a few milliseconds. Like other types of explosions, a blast wave can ...