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Polymorphous light eruption (PLE) presents with itchy red small bumps on sun-exposed skin, particularly face, neck, forearms and legs. [1] It generally appears 30 minutes to a few hours after sun exposure and may last between one and 14 days. [3] The bumps may become small blisters or plaques and may appear bloody, [3] often healing with ...
Afamelanotide, sold under the brand name Scenesse, is a medication used to prevent phototoxicity and to reduce pain from light exposure for people with erythropoietic protoporphyria. [ 1 ] [ 2 ] [ 4 ] It is a melanocortin 1 receptor (MC 1 receptor) agonist [ 1 ] and a synthetic peptide and analogue of α-melanocyte stimulating hormone . [ 1 ]
Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy is a skin condition that occurs most often in women receiving cobalt radiotherapy for internal cancer. [ 3 ] : 39–40
An example of primary photodermatoses is Polymorphous light eruption. Polymorphous light eruption is the most common type of photodermatoses. It is most likely due to an abnormal immune system reaction to the sun. Polymorphous light eruption occurs in approximately 10 to 20 percent [3] of otherwise healthy individuals, so it is a relatively common
Porfimer sodium is a drug used to treat some types of cancer. When absorbed by cancer cells and exposed to light, porfimer sodium becomes active and kills the cancer cells. It is a type of photodynamic therapy (PDT) agent and also called Photofrin. [14]
Extracts from Camptotheca (the "happy tree" or "cancer tree") were used to develop the chemotherapeutic drug Topotecan. Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans. [1] [2]
Solar urticaria is an immunoglobulin E-mediated hypersensitivity that can be introduced through primary or secondary factors, or induced by exogenous photosensitization. [15] [16] Primary SU is believed to be a type I hypersensitivity (a mild to severe reaction to an antigen including anaphylaxis) in which an antigen, or substance provoking an immune response, is "induced by UV or visible ...
Photoprotection is the biochemical process that helps organisms cope with molecular damage caused by sunlight.Plants and other oxygenic phototrophs have developed a suite of photoprotective mechanisms to prevent photoinhibition and oxidative stress caused by excess or fluctuating light conditions.