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It is usually a combination of a Bode magnitude plot, expressing the magnitude (usually in decibels) of the frequency response, and a Bode phase plot, expressing the phase shift. As originally conceived by Hendrik Wade Bode in the 1930s, the plot is an asymptotic approximation of the frequency response, using straight line segments .
Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...
Cell cycle analysis by DNA content measurement is a method that most frequently employs flow cytometry to distinguish cells in different phases of the cell cycle.Before analysis, the cells are usually permeabilised and treated with a fluorescent dye that stains DNA quantitatively, such as propidium iodide (PI) or 4,6-diamidino-2-phenylindole (DAPI).
Hendrik Wade Bode (/ ˈ b oʊ d i / BOH-dee, Dutch:; [1] December 24, 1905 – June 21, 1982) [1] was an American engineer, researcher, inventor, author and scientist, of Dutch ancestry. As a pioneer of modern control theory and electronic telecommunications he revolutionized both the content and methodology of his chosen fields of research.
The original model proposed by Graner and Glazier contains cells of two types, with different adhesion energies for cells of the same type and cells of a different type. Each cell type also has a different contact energy with the medium, and the cell volume is assumed to remain close to a target value. The Hamiltonian is formulated as:
The repair model, instead of the target theory, emphasizes how a cell utilizes said cell’s repair mechanisms up to the limit of the cell’s repair machinery (the end of the shoulder). After the limit of the cell’s machinery is reached, the repair model generally notes that if any damage is left unhealed the dying process will be initiated.
Mixed co-culture is the simplest co-culture method, where two types of cells are in direct contact within a single culture compartment at the desired cell ratio. [47] Cells can communicate by paracrine and juxtacrine signaling, but separated treatments and downstream analysis of a single cell type are not readily feasible due to the completely ...
A cell line can be defined as a permanently established cell culture which will propagate forever. Investigators mostly get cell lines from other investigators or from cell banks (such as the American Type Culture Collection) , because its much easier than creating new one. In special cases, investigators are obligated to establish a cell line.