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  2. Intracellular pH - Wikipedia

    en.wikipedia.org/wiki/Intracellular_pH

    Intracellular pH is typically lower than extracellular pH due to lower concentrations of HCO 3 −. [9] A rise of extracellular (e.g., serum) partial pressure of carbon dioxide (pCO 2) above 45 mmHg leads to formation of carbonic acid, which causes a decrease of pH i as it dissociates: [10]

  3. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acid–base imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [16]).

  4. Esophageal pH monitoring - Wikipedia

    en.wikipedia.org/wiki/Esophageal_pH_Monitoring

    Esophageal pH monitoring is performed for 24 or 48 hours and at the end of recording, a patient's tracing is analyzed and the results are expressed using six standard components. Of these 6 parameters, a pH score called Composite pH Score or DeMeester Score has been calculated, which is a global measure of esophageal acid exposure. A Demeester ...

  5. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    The Henderson–Hasselbalch equation can be used to model these equilibria. It is important to maintain this pH of 7.4 to ensure enzymes are able to work optimally. [10] Life threatening Acidosis (a low blood pH resulting in nausea, headaches, and even coma, and convulsions) is due to a lack of functioning of enzymes at a low pH. [10]

  6. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    The pH of tears shift throughout a waking day, rising "about 0.013 pH units/hour" until a prolonged closed-eye period causes the pH to fall again. [15] Most healthy individuals have tear pH in the range of 7.0 to 7.7, where bicarbonate buffering is the most significant, but proteins and other buffering components are also present that are ...

  7. Reference range - Wikipedia

    en.wikipedia.org/wiki/Reference_range

    The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.

  8. Hemodynamics - Wikipedia

    en.wikipedia.org/wiki/Hemodynamics

    Typical values for the viscosity of normal human plasma at 37 °C is 1.4 mN·s/m 2. [3] The viscosity of normal plasma varies with temperature in the same way as does that of its solvent water [ 4 ] ;a 3°C change in temperature in the physiological range (36.5°C to 39.5°C)reduces plasma viscosity by about 10%.

  9. Ringer's solution - Wikipedia

    en.wikipedia.org/wiki/Ringer's_solution

    Ringer's solution is frequently administered to human and veterinary patients for intravenous or subcutaneous hydration and to expand the vascular compartment in hypovolemia. It is also use in in vitro experiments on organs or tissues, such as in vitro muscle testing .

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