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  2. Osteomalacia - Wikipedia

    en.wikipedia.org/wiki/Osteomalacia

    Proximal muscles are weak, and there is difficulty in climbing upstairs and getting up from a squatting position. [13] As a result of demineralization, the bones become less rigid. Physical signs include deformities like triradiate pelvis [ 14 ] and lordosis .

  3. Inclusion body myositis - Wikipedia

    en.wikipedia.org/wiki/Inclusion_body_myositis

    Weakness comes on slowly (over months to years) in an asymmetric manner and progresses steadily, leading to severe weakness and wasting of arm and leg muscles. IBM is more common in men than women. [10] Patients may become unable to perform activities of daily living and most require assistive devices within 5 to 10 years of symptom onset.

  4. Lambert–Eaton myasthenic syndrome - Wikipedia

    en.wikipedia.org/wiki/Lambert–Eaton_myasthenic...

    The weakness from LEMS typically involves the muscles of the proximal arms and legs (the muscles closer to the trunk). In contrast to myasthenia gravis, the weakness affects the legs more than the arms. This leads to difficulties climbing stairs and rising from a sitting position.

  5. Myopathy - Wikipedia

    en.wikipedia.org/wiki/Myopathy

    Polymyositis produces muscle weakness. It can often be treated by drugs like corticosteroids or immunosuppressants. Inclusion body myositis is a slowly progressive disease that produces weakness of hand grip and straightening of the knees. No effective treatment is known. (M60.9) Benign acute childhood myositis (M61) Myositis ossificans

  6. Inflammatory myopathy - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_myopathy

    The usual criteria for a diagnosis of PM are weakness in muscles of the head, neck, trunk, upper arms or upper legs; raised blood serum concentrations of some muscle enzymes such as creatine kinase; unhealthy muscle changes on electromyography; and biopsy findings of (i) muscle cell degeneration and regeneration and (ii) chronic inflammatory ...

  7. Hypokalemic periodic paralysis - Wikipedia

    en.wikipedia.org/wiki/Hypokalemic_periodic_paralysis

    Hypokalemic periodic paralysis is a condition that causes episodes of extreme muscle weakness typically beginning in childhood or adolescence. Most often, these episodes involve a temporary inability to move muscles in the arms and legs. Attacks cause severe weakness or paralysis that usually lasts from hours to days.

  8. Neuromuscular disease - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular_disease

    Symptoms of neuromuscular disease may include numbness, paresthesia, muscle atrophy, a pseudoathletic appearance, exercise intolerance, myalgia (muscle pain), fasciculations (muscle twitches), myotonia (delayed muscle relaxation), hypotonia (lack of resistance to passive movement), fixed muscle weakness (a static symptom), or premature muscle ...

  9. Vitamin D deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_deficiency

    It can also worsen osteomalacia and osteoporosis in adults, increasing the risk of bone fractures. [1] [4] Muscle weakness is also a common symptom of vitamin D deficiency, further increasing the risk of falls and bone fractures in adults. [1] Vitamin D deficiency is associated with the development of schizophrenia. [5]

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