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Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. [10] An epileptic seizure is the clinical manifestation of an abnormal, excessive, and synchronized electrical discharge in the neurons. [1] The occurrence of two or more unprovoked seizures defines epilepsy. [11]
In newly diagnosed epilepsy, magnetic resonance imaging (MRI) can detect brain lesion in up to 12 to 14% of persons with epilepsy. [31] However, for those with chronic epilepsy, MRI can detect brain lesion in 80% of the persons with epilepsy. [31] 3-Tesla MRI scan is advised for those with evidence of focal epilepsy such as temporal lobe ...
Status epilepticus (SE), or status seizure, is a medical condition with abnormally prolonged seizures. It can have long-term consequences, [ 3 ] manifesting as a single seizure lasting more than a defined time (time point 1), or 2 or more seizures over the same period without the person returning to normal between them.
Complex partial status epilepticus (CPSE) is one of the non-convulsive forms of status epilepticus, a rare form of epilepsy defined by its recurrent nature. CPSE is characterized by seizures involving long-lasting stupor, staring and unresponsiveness. [1] Sometimes this is accompanied by motor automatisms, such as eye twitching. [2]
Epilepsia partialis continua is a rare [1] type of brain disorder in which a patient experiences recurrent motor epileptic seizures that are focal (hands and face), and recur every few seconds or minutes for extended periods (days to years).
Transient amnesia can be the principal manifestation of epilepsy. This diagnosis, however, is "seldom suspected by clinicians and remains controversial". [4] TEA is "almost always misdiagnosed" according to a leading authority. [9] In the largest study to date (2007) "Epilepsy was the initial specialist diagnosis in only 12 of 50 cases."
After an episode of PRES, even when it was associated with seizure activity, only a small proportion of people remain at risk of ongoing seizures and the majority can eventually discontinue anticonvulsant treatment. [3] Approximately 3% of those with PRES will develop late, recurrent seizures with 1% developing a chronic seizure disorder .
Strokes, brain bleeds, and traumatic brain injury can all also lead to epilepsy if seizures re-occur. If the first seizure occurs more than 7 days following a stroke, there is a higher chance of the person developing epilepsy. [27] Post-stroke epilepsy accounts for 30%-50% of new epilepsy cases. [27]
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