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Tetraplegia, also known as quadriplegia, is defined as the dysfunction or loss of motor and/or sensory function in the cervical area of the spinal cord. [1] A loss of motor function can present as either weakness or paralysis leading to partial or total loss of function in the arms, legs, trunk, and pelvis.
Spastic tetraplegia, thin corpus callosum, and progressive microcephaly (often referred to by its acronym SPATCCM) is a rare autosomal recessive disease caused by mutations in the SLC1A4 gene encoding the ASCT1 protein.
The part of the spinal cord that was damaged corresponds to the spinal nerves at that level and below. Injuries can be cervical 1–8 (C1–C8), thoracic 1–12 (T1–T12), lumbar 1–5 (L1–L5), [9] or sacral (S1–S5). [10] A person's level of injury is defined as the lowest level of full sensation and function. [11]
The cervical spinal nerve 1 (C1) is a spinal nerve of the cervical segment. [1] C1 carries predominantly motor fibres, but also a small meningeal branch that supplies sensation to parts of the dura around the foramen magnum (via dorsal rami). It originates from the spinal column from above the cervical vertebra 1 (C1). [2]
Spastic quadriplegia, also known as spastic tetraplegia, is a subset of spastic cerebral palsy that affects all four limbs (both arms and legs). Compared to quadriplegia , spastic tetraplegia is defined by spasticity of the limbs as opposed to strict paralysis .
Therefore, initial survivors of atlantooccipital dislocation may show severe and variable neurologic deficits, including reversible or irreversible tetraplegia, multiple cranial nerve deficits, loss of consciousness, and recurrent respiratory and/or cardiac arrests. Children are more likely to survive with neurologic compromise than adults.
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A common goal of surgical reconstruction of the arms in patients with tetraplegia is to restore elbow extension, key pinch and palmar grip. Restoration of these functions, results in increasing a patient's independence. [24] Palmar grip. Elbow extension is an important part of upper limb surgical reconstruction in patients with tetraplegia.