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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
This is a list of encyclopedias in the French language. Printed (paper) Digital (online) Both* *This usually means that volumes of the encyclopaedia were originally printed on paper, but at some point (usually in the 1990s or early 2000s), the encyclopaedia has been digitised and made available in whole or in part in electronic form (usually online, but not necessarily).
On 7 March 2013, France 2 aired an eight-minute investigative report purporting to expose a weapons smuggling channel from Serbia to France. The report authors, journalists Franck Genauzeau and Régis Mathé, traveled to Serbia in February 2013 where they filmed a story claiming that Serbia is a hub for international weapons smuggling.
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2C-iBu is a highly potent and robustly efficacious serotonin 5-HT 2A receptor agonist. [4] Its EC 50 Tooltip half-maximal effective concentration values are 1.3 nM for calcium mobilization and 57.5 nM for β-arrestin-2 recruitment, whereas its E max Tooltip maximal efficacy values are 103% for calcium mobilization and 77% for β-arrestin-2 recruitment relative to serotonin. [4]
meta-Chlorophenylbiguanide (1-(3-Chlorophenylbiguanide, m-CPBG) is an allosteric agonist and modulator of the 5-HT 3 receptor [1] [2] [3] and an antagonist of the α 2A-adrenergic receptor. [4] It has anxiogenic , emetic and hypothermic effects in animal studies.
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