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Endothelial protein C receptor (EPCR) also known as activated protein C receptor (APC receptor) is a protein that in humans is encoded by the PROCR gene. [ 5 ] [ 6 ] [ 7 ] PROCR has also recently been designated CD201 ( cluster of differentiation 201).
CD201: Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor), is a protein encoded by the PROCR gene. Mutations in this gene have been associated with venous thromboembolism, myocardial infarction and late fetal loss during pregnancy.
The biologic instructions for synthesising protein C in humans are encoded in the gene officially named "protein C (inactivator of coagulation factors Va and VIIIa)". The gene's symbol approved by the HUGO Gene Nomenclature Committee is "PROC" from "protein C". It is located on the second chromosome (2q13-q14) and comprises nine exons.
The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes.
Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein–Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. [5]
Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. [5] CCR6 has also recently been designated CD196 (cluster of differentiation 196). The gene is located on the long arm of Chromosome 6 (6q27) on the Watson (plus) strand.
Spokeo analyzed state government information and other historical sources to compile this list of stories behind every state's nickname.
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors . This receptor binds and responds to a variety of chemokines, including eotaxin ( CCL11 ), eotaxin-3 ( CCL26 ), MCP-3 ( CCL7 ), MCP-4 ( CCL13 ), and RANTES ( CCL5 ).