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  2. Syphilis in sub-Saharan Africa - Wikipedia

    en.wikipedia.org/wiki/Syphilis_in_sub-Saharan_Africa

    Over 10 million people are afflicted, mainly in sub-Saharan Africa and Asia. In the former, data gathered in 2019 from numerous studies concluded a total prevalence of about 2.9% among pregnant women. Pregnant women in East and Southern Africa typically ran higher, with respectively averages of 3.2% and 3.6%. It appeared to have decreased some ...

  3. Diagnosis of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Diagnosis_of_HIV/AIDS

    Nucleic-acid-based tests amplify and detect one or more of several target sequences located in specific HIV genes, such as HIV-I GAG, HIV-II GAG, HIV-env, or the HIV-pol. [33] [34] Since these tests are relatively expensive, the blood is screened by first pooling some 8–24 samples and testing these together; if the pool tests positive, each ...

  4. Tuskegee Syphilis Study - Wikipedia

    en.wikipedia.org/wiki/Tuskegee_Syphilis_Study

    The Tuskegee Study of Untreated Syphilis in the Negro Male [1] (informally referred to as the Tuskegee Experiment or Tuskegee Syphilis Study) was a study conducted between 1932 and 1972 by the United States Public Health Service (PHS) and the Centers for Disease Control and Prevention (CDC) on a group of nearly 400 African American men with syphilis.

  5. HIV/AIDS in Africa - Wikipedia

    en.wikipedia.org/wiki/HIV/AIDS_in_Africa

    Prevalence of HIV/AIDS in Africa, total (% of population ages 15–49), in 2021 (World Bank) HIV / AIDS originated in the early 20th century and remains a significant public health challenge, particularly in Africa. Although the continent constitutes about 17% of the world's population, it bears a disproportionate burden of the epidemic. As of 2023, around 25.6 million people in sub-Saharan ...

  6. Venereal Disease Research Laboratory test - Wikipedia

    en.wikipedia.org/wiki/Venereal_Disease_Research...

    The MHA-TP is used to confirm a syphilis infection after another method tests positive for the syphilis bacteria. The MHA-TP test detects antibodies to the bacteria that cause syphilis and can be used to detect syphilis in all stages, except during the first 3 to 4 weeks. This test is not done on spinal fluid.

  7. Neurosyphilis - Wikipedia

    en.wikipedia.org/wiki/Neurosyphilis

    All patients with syphilis should be tested for HIV infection. [5] All cases of syphilis should be reported to public health authorities and public health departments can aid in partner notification, testing, and determining need for treatment. [26] The treatment success is measured with a fourfold drop in the nontreponemal antibody test.

  8. Treponema pallidum particle agglutination assay - Wikipedia

    en.wikipedia.org/wiki/Treponema_pallidum...

    Often a plastic test plate containing many small "wells" is used as the test dish so that many patients may be tested at the same time but their results can be kept separate from each other. Please note the image (Fig 1) of the wells on the test plate and the positive and negative test results look different. [1] For primary syphilis, TPPA has ...

  9. History of syphilis - Wikipedia

    en.wikipedia.org/wiki/History_of_syphilis

    [8] [9] Phylogenetic analyses in 2008 [10] [11] and 2024 showed syphilis originated in the Americas around 9000 years ago, adding to a preponderance of archaeological evidence showing the disease existed in the Americas prior to the arrival of Europeans, [3] and the historical evidence documenting the arrival of syphilis in Europe coinciding ...

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