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Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
Harry Raymond Eastlack, Jr. (17 November 1933 – 11 November 1973) was the subject of the most recognized case of fibrodysplasia ossificans progressiva (FOP) from the 20th century. His case is also particularly acknowledged, by scientists and researchers, for his contribution to medical advancement.
Carol Orzel (April 20, 1959 – February 2018) was an American woman with fibrodysplasia ossificans progressiva (FOP). She advocated for research into FOP and was an activist for disability rights . Before her death, she requested that her skeleton be displayed in the Mütter Museum .
Some of the patients initially diagnosed with FOP were found to have a distinctly different manifestation of symptoms, though, like FOP, the disease still resulted in heterotopic ossification (formation of bone tissue outside the skeleton). None of the patients had congenital abnormalities of the big toe, which is a diagnostic feature for FOP.
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Pages in category "Fibrodysplasia ossificans progressiva" The following 6 pages are in this category, out of 6 total. This list may not reflect recent changes. E.
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