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Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic index. For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug ...
Topical drug delivery (TDD) is a route of drug administration that allows the topical formulation to be delivered across the skin upon application, hence producing a localized effect to treat skin disorders like eczema. [1] [2] The formulation of topical drugs can be classified into corticosteroids, antibiotics, antiseptics, and anti-fungal.
A. The AAPS Journal; AAPS PharmSciTech; Acta Facultatis Pharmaceuticae Universitatis Comenianae; Advanced Drug Delivery Reviews; Advances in Therapy; Alimentary Pharmacology & Therapeutics
Pharmacology: Taylor and Francis Group: English: 2006–present Expert Opinion on Drug Metabolism & Toxicology: Pharmacology: Taylor and Francis Group: English: 2005–present Expert Opinion on Drug Safety: Pharmacology: Informa: English: 2002–present Expert Opinion on Emerging Drugs: Pharmacology: Informa: English: 1996–present Expert ...
Drug delivery systems have been around for many years, but there are a few recent applications of drug delivery that warrant 1. Drug delivery to the brain: Many drugs can be harmful when administered systemically; the brain is very sensitive to medications and can easily cause damage if a drug is administered directly into the bloodstream.
In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration. Routes can also be classified based ...
Drug Delivery is a peer-reviewed open access medical journal covering research on all aspects of drug delivery, a core aspect of drug development. It is published by Taylor & Francis and since 2009 the editor-in-chief is Vladimir Torchilin. Biochemist Alfred Stracher founded the journal in 1997 and was its editor-in-chief until his death in ...
When used as a delivery system, the ability to induce instability in the construct is commonly exploited allowing the selective release of the encapsulated therapeutic agent in close proximity to the target tissue/cell in vivo. This nanocarrier system is commonly used in anti-cancer treatments as the acidity of the tumour mass caused by an over ...