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In histology (microscopic anatomy), the lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic scale. The hepatic lobule is a building block of the liver tissue , consisting of portal triads, hepatocytes arranged in linear cords between a capillary network, and a central vein .
Centrilobular necrosis (CN) is a nonspecific histopathological observation brought on by hepatotoxins like acetaminophen (paracetamol), [1] thioacetamide, tetrachloride, [2] cardiac hepatopathy due to acute right sided cardiac failure, and congestive hepatic injury in veno-occlusive disease, [3] or hypoxic injury due to ischemia. [2]
In microanatomy, the central vein of liver (or central venule) [1] is a vein at the center of each hepatic lobule. [2] It receives the blood mixed in the liver sinusoids to drain it into hepatic veins .
The liver is the only human internal organ capable of natural regeneration of lost tissue; as little as 25% of a liver can regenerate into a whole liver. [75] This is, however, not true regeneration but rather compensatory growth in mammals. [ 76 ]
Liver showing chronic passive congestion associated with tricuspid valve incompetence. So called 'nutmeg liver', Split nutmeg, for those who have never seen this appearance. Close up of congested liver showing the 'nutmeg' appearance. Congestive hepatopathy, is liver dysfunction due to venous congestion, usually due to congestive heart failure.
The bare area of the liver is found on the posterosuperior surface of the right lobe of the liver. [1] This lies close to the thoracic diaphragm. It is the only part of the liver that has no peritoneal covering. [1] [2] It lies between the two layers of the coronary ligament, as well as the right triangular ligament. [1]
Savannah Chrisley and Bobby Bones Shutterstock (2) The Growing Up Chrisley alum added: “All I ask is for mutual respect and decency. But for now I will meet you where you came for me.”
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein synthesis; Protein storage; Transformation of carbohydrates; Synthesis of cholesterol, bile salts and phospholipids; Detoxification, modification, and excretion of exogenous and endogenous substances