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If you’ve been prescribed metformin, it may be because you have prediabetes, type 2 diabetes, gestational diabetes, weight gain issues caused by antipsychotic medication or polycystic ovary ...
Prediabetes, often considered the step before diabetes, is when you have higher than usual blood glucose (blood sugar) levels. Your levels aren’t high enough to be classified as type 2 diabetes.
Some studies have shown delayed progression to diabetes in predisposed patients through prophylactic use of metformin, [17] [5] rosiglitazone, [18] or valsartan. [19] Lifestyle interventions are, however, more effective than metformin alone at preventing diabetes regardless of weight loss, [20] though evidence suggests that lifestyle interventions and metformin together can be effective ...
Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain.
In individuals with prediabetes, a 2019 systematic review comparing the effects of metformin with other interventions in the reduction of risk of developing type 2 diabetes found moderate-quality evidence that metformin reduced the risk of developing type 2 diabetes when compared to diet and exercise or a placebo. [49]
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
One of the most common drugs used in T2D, metformin is the drug of choice to help patients lower their blood sugar levels. Metformin is an example of a class of medicine called biguanides. [35] The medication works by reducing the new creation of glucose from the liver and by reducing absorption of sugar from food. [35]
Metformin is approved for prediabetes and type 2 diabetes and has become one of the more commonly prescribed medications for insulin resistance. [60] The Diabetes Prevention Program (DPP) showed that exercise and diet were nearly twice as effective as metformin at reducing the risk of progressing to type 2 diabetes. [61]
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