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  2. Hodge conjecture - Wikipedia

    en.wikipedia.org/wiki/Hodge_conjecture

    In mathematics, the Hodge conjecture is a major unsolved problem in algebraic geometry and complex geometry that relates the algebraic topology of a non-singular complex algebraic variety to its subvarieties.

  3. Chromosome conformation capture - Wikipedia

    en.wikipedia.org/wiki/Chromosome_conformation...

    Each eigenvector corresponds to a set of loci, which are not necessarily linearly contiguous, that share structural features. [65] A significant confounding factor in 3C technologies is the frequent non-specific interactions between genomic loci that occur due to random polymer behavior. An interaction between two loci must be confirmed as ...

  4. Open problem - Wikipedia

    en.wikipedia.org/wiki/Open_problem

    [2] [3] An important open mathematics problem solved in the early 21st century is the Poincaré conjecture. Open problems exist in all scientific fields. For example, one of the most important open problems in biochemistry is the protein structure prediction problem [4] [5] – how to predict a protein's structure from its sequence.

  5. ImageJ - Wikipedia

    en.wikipedia.org/wiki/ImageJ

    ImageJ is a Java-based image processing program developed at the National Institutes of Health and the Laboratory for Optical and Computational Instrumentation (LOCI, University of Wisconsin). [ 2 ] [ 3 ] Its first version, ImageJ 1.x, is developed in the public domain , while ImageJ2 and the related projects SciJava , ImgLib2 , and SCIFIO are ...

  6. Genome-wide association study - Wikipedia

    en.wikipedia.org/wiki/Genome-wide_association_study

    An illustration of a Manhattan plot depicting several strongly associated risk loci. Each dot represents a SNP , with the X-axis showing genomic location and Y-axis showing association level . This example is taken from a GWA study investigating kidney stone disease , so the peaks indicate genetic variants that are found more often in ...

  7. Problem finding - Wikipedia

    en.wikipedia.org/wiki/Problem_finding

    Problem discovery is an unconscious process which depends upon knowledge whereby an idea enters one's conscious awareness, problem formulation is the discovery of a goal; problem construction involves modifying a known problem or goal to another one; problem identification represents a problem that exists in reality but needs to be discovered ...

  8. Ludics - Wikipedia

    en.wikipedia.org/wiki/Ludics

    By abstracting the notion of formulae and focusing on their concrete uses—that is distinct occurrences—it provides an abstract syntax for computer science, as loci can be seen as pointers on memory. The primary achievement of ludics is the discovery of a relationship between two natural, but distinct notions of type, or proposition.

  9. Locus (mathematics) - Wikipedia

    en.wikipedia.org/wiki/Locus_(mathematics)

    Each curve in this example is a locus defined as the conchoid of the point P and the line l.In this example, P is 8 cm from l. In geometry, a locus (plural: loci) (Latin word for "place", "location") is a set of all points (commonly, a line, a line segment, a curve or a surface), whose location satisfies or is determined by one or more specified conditions.