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In a 5-day study, mice were administered up to 10 mg/kg apomorphine subcutaneously daily. No adverse effects were observed other than a slight increase in dopamine levels. [ 28 ] Notably, apomorphine is used in veterinary clinics as an emetic due to severe off-target effects that lead to vomiting.
Apomorphine, sold under the brand name Apokyn among others, is a type of aporphine having activity as a non-selective dopamine agonist which activates both D 2-like and, to a much lesser extent, D 1-like receptors. [2] It also acts as an antagonist of 5-HT 2 and α-adrenergic receptors with high affinity.
Thujone (/ ˈ θ uː dʒ oʊ n / ⓘ [2]) is a ketone and a monoterpene that occurs predominantly in two diastereomeric forms: (−)-α-thujone and (+)-β-thujone. [3] [4]Though it is best known as a chemical compound in the spirit absinthe, it is only present in trace amounts and is unlikely to be responsible for the spirit's purported stimulant and psychoactive effects.
On January 14, 2010, the Russian government issued a statement including 23 synthetic cannabinoids found in smoking blends Hawaiian Rose and Blue Lotus on the list of prohibited narcotic and psychotropic substances. [145] About 780 new psychoactive substances were added to the list from 2011 to 2014.
Acacia falcata, Psychoactive, [16] but less than 0.02% alkaloids [15] Vachellia farnesiana, Traces of 5-MeO-DMT [25] in fruit. β-methyl-phenethylamine, flower. [26] Ether extracts about 2–6% of the dried leaf mass. [27] Alkaloids are present in the bark [28] and leaves. [29] Acacia flavescens, Strongly Psychoactive, Bark [citation needed]
Blue lotus may refer to: Nymphaea nouchali var. caerulea , a water lily in the genus Nymphaea that was known to the Ancient Egyptian civilizations Nymphaea nouchali , a water lily of genus Nymphaea that is native to southern and eastern parts of Asia, containing the sedating alkaloids apomorphine and nuciferine
Amantadine was initially developed to prevent replication of the influenza A virus. [18] Its main clinical use today is treatment of Parkinson's disease. [18] Other uses include treatment of drug-induced extrapyramidal side effects, motor fluctuations during levodopa therapy in Parkinson's disease, traumatic brain injury, and autistic spectrum disorders.
The LSD is taken first, followed by the MDMA 4 hours later and then 2C-B is taken 2 hours after the MDMA ( so 6 hours after the LSD ). MDMA can be replaced by 6-APB, 5-APB, 6-MAPB or 5-MAPB, in this case the Empathogen is taken 2 hours after the LSD, while 2C-B may be replaced by 2C-C, 2C-D or 2C-B-FLY.