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Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
Rare (<0.1%) adverse effects include: Urinary retention; Prolonged QT interval; Torsades de Pointes; Ataxia; Breast enlargement or engorgement; Lactation; Cardiospasm
The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
The CDC reported recently that heroin-related overdose deaths jumped 39 percent nationwide between 2012 and 2013, surging to 8,257. In the past decade, Arizona’s heroin deaths rose by more than 90 percent. New York City had 420 heroin overdose deaths in 2013 — the most in a decade.
Vilazodone acts as a serotonin reuptake inhibitor (IC 50 = 2.1 nM; K i = 0.1 nM) and 5-HT 1A receptor partial agonist (IC 50 = 0.2 nM; IA = ~60–70%). [ 14 ] [ 26 ] It has negligible affinity for other serotonin receptors such as 5-HT 1D , 5-HT 2A , and 5-HT 2C , [ 26 ] [ 27 ] as well as the norepinephrine and dopamine transporters (K i = 56 ...
“The dangers of an increase of fentanyl use in our region could have catastrophic effects.”
The fire station shared on Facebook, " Due to the dog's slow breathing, pinpoint pupils, and lethargy, the firefighters administered a small dose of Narcan and contacted an emergency veterinarian ...