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Vitamin B 3, also known as niacin, includes both nicotinamide as well as nicotinic acid, both of which function in many biological oxidization and reduction reactions within the body. Niacin is involved in the synthesis of fatty acids and cholesterol , known mediators of brain biochemistry, and in effect, of cognitive function.
The axolotl is less commonly used than other vertebrates, but is still a classical model for examining regeneration and neurogenesis. Though the axolotl has made its place in biomedical research in terms of limb regeneration, [19] [20] the model organism has displayed a robust ability to generate new neurons following damage.
Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). [1] This occurs in all species of animals except the porifera (sponges) and placozoans . [ 2 ]
Synaptogenesis is the formation of synapses between neurons in the nervous system.Although it occurs throughout a healthy person's lifespan, an explosion of synapse formation occurs during early brain development, known as exuberant synaptogenesis. [1]
Neuroenhancement or cognitive enhancement is the experimental use of pharmacological or non-pharmacological methods intended to improve cognitive and affective abilities in healthy people who do not have a mental illness.
The amino acid creatine, commonly used as a supplement to improve the performance of bodybuilders, has been studied for its potential antidepressant properties. A review found that creatine "has the potential to improve these disruptions [of brain metabolism] in some patients, and early clinical trials indicate that it may have efficacy as an ...
Elizabeth Gould (born 1962) [1] is an American neuroscientist and the Dorman T. Warren Professor of Psychology at Princeton University. [ 2 ] [ 3 ] She demonstrated adult neurogenesis in the mammalian hippocampus , and subsequently found evidence for neurogenesis in adult humans that has been challenged by other researchers in the field.
Hippocampal neurogenesis. In the subgranular zone in the dentate gyrus of the hippocampus, NSCs differentiate into granule cells. These new granule cells are implicated in memory formation and learning. [3] The number of granule cells generated in the dentate gyrus each month is approximately 6% of the total population of dentate gyrus neurons. [3]