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Nanoscale iron particles are sub-micrometer particles of iron metal. [1] Due to their high catalytic activity, low toxicity, and strong adsorption capacity, iron-based nanoparticles are widely utilized in drug delivery, magnetic targeting, gene therapy, and environmental remediation. [2]
Labelling cells (e.g. stem cells, dendritic cells) with iron oxide nanoparticles is an interesting new tool to monitor such labelled cells in real time by magnetic resonance tomography. [13] [14] Some forms of Iron oxide nanoparticle have been found to be toxic and cause transcriptional reprogramming. [15] [16]
Nanoparticles can also be functionalized with polymers or oligomers to sterically stabilize the nanoparticles by providing a protective layer that prevents the nanoparticles from interacting with each other. [8] Alloys of two metals, called bimetallic nanoparticles, are used to create synergistic effects on catalysis between the two metals. [9]
Nitrate reduction by iron powder is observed at pH ≤ 4. [11] Ammonia is the end product. Using nanoscale iron, Nitrogen gas (N 2) is the product. [12] Nitrated aromatics are reduced by bulk iron. [7] [13] [14] Chlorinated pesticides such as DDT, DDD, and DDE. The rates of dechlorination are enhanced by the surfactant Triton X-114. [15]
Nanoparticles are classified as having at least one of its dimensions in the range of 1-100 nanometers (nm). [2] The small size of nanoparticles allows them to have unique characteristics which may not be possible on the macro-scale. Self-assembly is the spontaneous organization of smaller subunits to form larger, well-organized patterns. [3]
Ferrite nanoparticles or iron oxide nanoparticles (iron oxides in crystal structure of maghemite or magnetite) are the most explored magnetic nanoparticles up to date.Once the ferrite particles become smaller than 128 nm [22] they become superparamagnetic which prevents self agglomeration since they exhibit their magnetic behavior only when an external magnetic field is applied.
Nanoparticles can enhance the effects of traditional antibiotics which a bacterium may have become resistant to, and decrease the overall minimum inhibitory concentration (MIC) required for a drug. Silver nanoparticles improve the activity of amoxicillin , penicillin , and gentamicin in bacteria by altering membrane permeability and improving ...
This is accomplished by coating the outside of a nanoparticle with iron oxide (allowing for easy tracking with an MRI machine), then once the area of the tumor is coated with the drug-filled nanoparticles, the nanoparticles can be activated using resonant light waves to release the drug.