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  2. US FDA mandates label updates on CAR-T cancer therapies - AOL

    www.aol.com/news/us-fda-mandates-label-updates...

    US FDA mandates label updates on CAR-T cancer therapies. April 18, 2024 at 6:39 PM (Reuters) - The U.S. Food and Drug Administration said on Thursday cancer therapies that use CAR-T technology ...

  3. Elexacaftor/tezacaftor/ivacaftor - Wikipedia

    en.wikipedia.org/wiki/Elexacaftor/tezacaftor/...

    FDA approval for children aged 6–11 was added in January 2021, after a third clinical trial was completed. [33] In 2023, approval was extended to children 2–5. [34] The US Food and Drug Administration (FDA) granted the application priority review, in addition to fast track, breakthrough therapy, and orphan drug designations.

  4. Bi-specific T-cell engager - Wikipedia

    en.wikipedia.org/wiki/Bi-specific_T-cell_engager

    Tarlatamab, sold under the brand name Imdelltra, is an anti-cancer medication used for the treatment of extensive-stage small cell lung cancer. [17] It is a bispecific T-cell engager that binds delta-like ligand 3 and CD3.

  5. Newly Published Data Indicates St. Jude Medical Trifecta ...

    www.aol.com/news/2013-03-19-newly-published-data...

    Conducted at 31 medical centers in the U.S., Canada and Europe, the study followed 1,014 eligible patients implanted with the Trifecta valve between 2007 and 2009 as part of a U.S. Food and Drug ...

  6. St. Jude Medical - Wikipedia

    en.wikipedia.org/wiki/St._Jude_Medical

    St. Jude Medical was founded in 1976 to further develop bi-leaflet artificial heart valves, which were originally created in 1972 at the University of Minnesota. [4] [5] St. Jude Medical's bi-leaflet valve was developed in large part by Dr. Demetre Nicoloff of the University of Minnesota and St. Jude Medical employee Don Hanson.

  7. Regeneron's blood cancer therapy faces setback as FDA ... - AOL

    www.aol.com/news/regenerons-blood-cancer-therapy...

    While odronextamab was on track to potentially become Regeneron's first blood cancer drug, it has a much smaller market opportunity of $200 million compared to other potential launches of the ...

  8. Ruthenium anti-cancer drugs - Wikipedia

    en.wikipedia.org/wiki/Ruthenium_anti-cancer_drugs

    Ruthenium anti-cancer drugs are coordination complexes of ruthenium complexes that have anticancer properties. They promise to provide alternatives to platinum -based drugs for anticancer therapy. [ 1 ] [ 2 ] Triruthenium carbonyl complexes containing maltol, ethylmaltol, N-phenyl and N-benzyl 4-pyridones show excellent anticancer activity.

  9. This Biotech Trifecta Could Revolutionize Cancer

    www.aol.com/news/2013-10-25-this-biotech...

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