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  2. Abbott's heart valve repair device gets FDA advisers' backing

    www.aol.com/news/abbotts-heart-valve-repair...

    Advisers to the U.S. Food and Drug Administration on Tuesday backed an approval for Abbott Laboratories' heart valve repair device that is designed for patients who are at risk of complications or ...

  3. Newly Published Data Indicates St. Jude Medical Trifecta ...

    www.aol.com/news/2013-03-19-newly-published-data...

    Conducted at 31 medical centers in the U.S., Canada and Europe, the study followed 1,014 eligible patients implanted with the Trifecta valve between 2007 and 2009 as part of a U.S. Food and Drug ...

  4. Abbott's heart valve repair device gains US FDA approval - AOL

    www.aol.com/news/abbotts-heart-valve-repair...

    By Puyaan Singh (Reuters) -Abbott Laboratories said on Tuesday the U.S. FDA has approved its heart valve repair device for patients with a potentially fatal heart disease, just months after rival ...

  5. Transcatheter aortic valve replacement - Wikipedia

    en.wikipedia.org/wiki/Transcatheter_aortic_valve...

    [31] [32] It was the first aortic valve device to receive FDA approval, in November 2011 for use in inoperable patients and in October 2012 for use in patients at high surgical risk. [33] The device is effective in improving functioning in patients with severe aortic stenosis.

  6. Edwards Lifesciences - Wikipedia

    en.wikipedia.org/wiki/Edwards_Lifesciences

    Edwards introduced the transcatheter heart valve (THV) replacement procedure to U.S. patients unable to undergo open-heart surgery with FDA approval of the SAPIEN transcatheter valve in 2011. [24] The indication was expanded in November 2012 to include patients at a high risk for death or serious complications associated with open-heart surgery ...

  7. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    In combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth-factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, as detected by an FDA-approved test, following recurrence on or after completing adjuvant ...

  8. US FDA mandates label updates on CAR-T cancer therapies - AOL

    www.aol.com/news/us-fda-mandates-label-updates...

    (Reuters) - The U.S. Food and Drug Administration said on Thursday cancer therapies that use CAR-T technology will require changes to the so-called "boxed warning" to highlight the serious risk of ...

  9. Lorcaserin - Wikipedia

    en.wikipedia.org/wiki/Lorcaserin

    There had been concern that lorcaserin could cause cardiac valvulopathy based upon the reports of subjects taking the drug in Phase 2 trials. However, a 2016 Phase 3 clinical trial found no statistically significant differences in valvulopathy rates compared to control, being 2.4% for the drug subjects and 2.0% for controls, and concluded that the drug was safe for the target population [9 ...