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Cypermethrin is very toxic to cats which cannot tolerate the therapeutic doses for dogs. [6] This is associated with UGT1A6 deficiency in cats, the enzyme responsible for metabolizing cypermethrin. As a consequence, cypermethrin remains much longer in the cat's organs than in dogs or other mammals and can be fatal in large doses.
Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8]It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
Contemporary commercial products for the topical treatment of flea infestations on pets contain pesticides such as imidacloprid, permethrin, and (S)-methoprene. All flea-control products are recommended to be used at least half-yearly because the lifecycle of flea can last up to a year. [ 5 ]
It is effective against fleas, ticks, chewing lice and mosquitoes. [1] The active ingredients are imidacloprid, permethrin, and pyriproxyfen. This product is toxic to cats, [2] and it is not recommended to use it on dogs which share an environment with cats. [1]
Warmer weather brings these nasty things out in full force, and they love dogs. Ticks are found everywhere, but are commonly found in long grass, woodlands, and areas with lots of wildlife.
Phenothrin, also called sumithrin and d-phenothrin, [2] is a synthetic pyrethroid that kills adult fleas and ticks.It has also been used to kill head lice in humans. d-Phenothrin is used as a component of aerosol insecticides for domestic use.
Flumethrin is used in products, such as flea and tick collars, to protect pets against fleas. [ 4 ] It is also used in the proprietary product, ″Bayvarol″, ″Polyvar Yellow″ which are veterinary treatments used by beekeepers against the parasitic mite Varroa destructor .
Typically various types of synthetic pyrethroids such as deltamethrin, cypermethrin, and permethrin are formulated in an oil or watery suspension suitable for application direct to the skin of animals at risk. [56]
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