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An Atrial septal defect is a relatively common heart malformation that occurs when the interatrial septum fails to develop properly. Persistence of the ostium secundum is the most common atrial septal defect. [3] Additionally, in a subset of the population, the foramen ovale is not overtly patent but the two septa have not fused.
Valve interstitial cells (VIC), cardiac valve interstitial cells, or also known as valvular interstitial cells (VICs), are the most prevalent cells in the heart valve leaflets, which are a type of mesenchymal stem cells (MSCs) and are responsible for maintaining the extracellular matrix that provides the mechanical properties of the heart valve.
Interstitial atoms (blue) occupy some of the spaces within a lattice of larger atoms (red) In materials science, an interstitial defect is a type of point crystallographic defect where an atom of the same or of a different type, occupies an interstitial site in the crystal structure.
Interstitial fibrosis of chronic ischemic heart disease, H&E stain, with associated relatively well organized myocardial bundles Subepicardial fibrosis (epicardium at top). Replacement fibrosis in myocardial infarction, typically being boundless, dense and not conforming to the other types.
The septum primum, a septum which grows down to separate the primitive atrium into the left atrium and right atrium, grows in size over the course of heart development.The primary interatrial foramen is the gap between the septum primum and the septum intermedium, which gets progressively smaller until it closes.
Three-dimensional schematic of the interstitium, a fluid-filled space supported by a network of collagen. In anatomy, the interstitium is a contiguous fluid-filled space existing between a structural barrier, such as a cell membrane or the skin, and internal structures, such as organs, including muscles and the circulatory system.
A VSD can cause a left-to-right shunt of blood flow in the heart and is one of the most common of the congenital heart defects. This type of shunt is an acyanotic disorder that can result in ventricular hypertrophy. [4] The alignment of interventricular septum and interatrial septum is disturbed in various congenital heart diseases. [5]
The atrioventricular septum is a septum of the heart between the right atrium (RA) and the left ventricle (LV). [1] [2]Although the name "atrioventricular septum" implies any septum between an atrium and a ventricle, in practice the divisions from RA to RV and from LA to LV are mediated by valves, not by septa.
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