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Linaclotide, like the endogenous guanylin and uroguanylin it mimics, is an agonist that activates the cell surface receptor of guanylate cyclase 2C (GC-C). [12] [4] [14] The medication binds to the surface of the intestinal epithelial cells. [4] Linaclotide is minimally absorbed and it is undetectable in the systemic circulation at therapeutic ...
A fact from Linaclotide appeared on Wikipedia's Main Page in the Did you know column on 27 September 2010 (check views).The text of the entry was as follows: Did you know... that linaclotide has shown promise in clinical trials as a treatment for irritable bowel syndrome with constipation, a condition that may affect as many as 10 million Americans?
Liraglutide, sold under the brand name Victoza among others, is an anti-diabetic medication used to treat type 2 diabetes, and chronic obesity. [6] [7] It is a second-line therapy for diabetes following first-line therapy with metformin.
Even so, compared to other health systems, such as hospitals and nursing homes, hospices remain infrequently and unevenly policed. HuffPost published this information about hospice inspections as a resource for consumers making decisions about end-of-life care. The indicators do not necessarily reflect quality of care.
Evidence-based nursing (EBN) is an approach to making quality decisions and providing nursing care based upon personal clinical expertise in combination with the most current, relevant research available on the topic.
The 2025 Leagues Cup will feature 18 of 30 MLS teams and all 18 clubs from LIGA MX, beginning July 29 to the Aug. 31 final. Tournament organizers announced the new format Thursday.
ATC code A06 Drugs for constipation is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
However, important limitations and considerations exist, especially for longer stays or frequent borrowing. Learn more in our guide to guest drivers and car insurance.