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Injecting any such mixture can cause serious damage to the skin, blood vessels, bone, and muscles, sometimes requiring limb amputation in long-term users. [10] This highly impure product may have received the name of krokodil due to the dire effects of the body which can readily be noticed.
A single dendrotoxin molecule associates reversibly with a potassium channel in order to exert its inhibitory effect. It is proposed that this interaction is mediated by electrostatic interactions between the positively charged amino acid residues in the cationic domain of dendrotoxin and the negatively charged residues in the ion channel pore.
In addition, tissue mineralization (bone, teeth) is promoted while tissue forming cells are in direct contact with bioglass materials. Whereas a material is considered bioactive if it has interaction with or effect on any cell tissue in the human body , pharmacological activity is usually taken to describe beneficial effects, i.e. the effects ...
The action of drugs on the human body (or any other organism's body) is called pharmacodynamics, and the body's response to drugs is called pharmacokinetics. The drugs that enter an individual tend to stimulate certain receptors, ion channels, act on enzymes or transport proteins. As a result, they cause the human body to react in a specific way.
The organs (e.g., liver) of the pufferfish can contain levels of tetrodotoxin sufficient to produce the described paralysis of the diaphragm and corresponding death due to respiratory failure. [51] Toxicity varies between species and at different seasons and geographic localities, and the flesh of many pufferfish may not be dangerously toxic.
The alligator likely suffered during the healing process, but continued to hunt and eat, experts say. “The section where those teeth should be in her jaw has been filled back in with bone and ...
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An 85-year-old woman has been killed in Florida after being attacked by a 10-foot alligator after she fought to wrestle her dog from its jaws.. The attack happened on the banks of a lake at the ...