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The heart is a muscular organ found in humans and other animals.This organ pumps blood through the blood vessels. [1] Heart and blood vessels together make the circulatory system. [2]
The first heart sound, or S 1, forms the "lub" of "lub-dub" and is composed of components M 1 (mitral valve closure) and T 1 (tricuspid valve closure). Normally M 1 precedes T 1 slightly.
A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart.A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart.
The heart derives from embryonic mesodermal germ layer cells that differentiate after gastrulation into mesothelium, endothelium, and myocardium.Heart induction occurs in the anterior mesoderm during gastrulation through interactions with adjacent endoderm (both extra-embryonic and definitive) mediated primarily by endogenous inhibitors of WNT signaling such as DKK1.
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart.
Percussive pacing, also known as transthoracic mechanical pacing, is the use of the closed fist, usually on the left lower edge of the sternum over the right ventricle in the vena cava, striking from a distance of 20 – 30 cm to induce a ventricular beat (the British Journal of Anaesthesia suggests this must be done to raise the ventricular pressure to 10–15 mmHg to induce electrical activity).
In humans the lungs are located in the chest on either side of the heart in the rib cage.They are conical in shape with a narrow rounded apex at the top, and a broad concave base that rests on the convex surface of the diaphragm. [1]
An artificial heart is a device that replaces the heart.Artificial hearts are typically used as a bridge to heart transplantation, but ongoing research aims to develop a device that could permanently replace the heart when a transplant—whether from a deceased human or, experimentally, from a genetically engineered pig—is unavailable or not viable.